Sorting and Secretion of Salivary Proteins

Intracellular transport and secretion of salivary proteins.

Intracellular transport and secretion of salivary proteins are major activities of salivary acinar cells. While the major intracellular pathway followed by salivary proteins following their synthesis has been described previously, there is only limited understanding of how this process is regulated at the molecular level. Studies of salivary proteins, especially proline-rich proteins, expressed...

The Function of Salivary Proteins and the Regulation of Their Secretion by Salivary Glands

• Salivary glycoproteins give saliva its characteristic physical properties and enable it to form a thin film over hard and soft tissues in the mouth. Oral health and homeostasis are dependent upon the functions performed by the salivary film and most of these functions, including lubrication, barrier function and microbial interactions, are in turn dependent upon salivary proteins. Some saliva...

Protein secretion: Sorting sweet sorting

How are proteins sorted to different destinations in eukaryotic cells? Until recently, it was generally thought that the constitutive flow of proteins to the cell surface occurs by default, and that proteins simply accumulate carbohydrate modifications as they pass sequentially through each compartment along the secretory pathway [1]. This hypothesis was supported by studies showing that inhibi...

Mechanisms of Salivary Secretion

functional study of p0 proteins of two cereal yellow dwarf viruses (cydv-rpv and cydv-rps) and identification of their cellular partner

نقش سرکوبگری پروتئین p0 در دو پولروویروس کوتولگی زردی غلات cydv-rpv) و (cydv-rps، متفاوت در شدت بیماریزایی، مورد مطالعه قرار گرفت. نتایج نشان داد که هر دو پروتئین p0 p0cy-rpv) و (p0cy-rps قادر به سرکوب خاموشی آر ان ای ایجاد شده توسط ترادف های تراژن سنس و تکرار معکوس در n. benthamiana هستند. نشان داده شد که هر دو پروتئین p0 می توانند تخریب پروتئین argonaute-1 را تسهیل کنند. علاوه بر این، تمایل م...